SMBE talk: Pervasive long-range linkage disequilibrium in D. melanogaster
I had the opportunity to present my latest paper draft on long range linkage disequilibrium in D. melanogaster at the SMBE 2015 meeting held in Vienna Austria. In this paper, Dmitri Petrov and I show that levels of LD both at short and long distances are elevated above neutral expectations in both Raleigh and Zambian populations of D. melanogaster. Furthermore, we find that levels of haplotype homozygosity are also elevated in both populations. Examination of the haplotype frequency spectra in the two populations reveals that signatures of soft sweeps are common in both populations, suggesting that soft sweeps are generic to multiple populations of Drosophila.
Here is a picture that Alex Cagan drew of me and my talk!